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Pancreatic Cancer

Pancreatic Cancer

Pancreatic cancer, arising in the pancreas, is considered one of the aggressive variants of cancer. Since the symptoms are quite difficult to recognize in the early stages, the prognosis can be challenging. Delayed diagnosis may lead to limited treatment options. The majority of pancreatic cancers manifest as exocrine tumors while they can be endocrine tumors too.

Some of the pancreatic cancer symptoms to watch out for may include:

  • Abdominal pain
  • Uncharacteristic weight loss
  • Jaundice.

Age, family history, smoking, and certain genetic syndromes are deemed the potent risk factors.

Having a clear and in-depth understanding of pancreatic cancer, its causes, symptoms, and risk factors can help you seek on-time diagnosis, treatment and prevention modalities.

The Types of Pancreatic Cancer

Pancreatic cancer manifests primarily in two types: exocrine and endocrine tumors. Exocrine tumors tend to originate from the glandular cells and are the most prevalent and aggressive form of pancreatic cancer. Comprising less than 5% of cases, endocrine pancreatic tumors are rare occurrences. Arising from the hormone-producing cells, endocrine pancreatic tumors tend to be less aggressive.

Exocrine Pancreatic Tumors

Exocrine Pancreatic Tumors

Exocrine tumors tend to originate from glandular cells and are the most prevalent and aggressive form of pancreatic cancer.

Endocrine Pancreatic Tumors

Endocrine Pancreatic Tumors

Comprising less than 5% of cases, endocrine pancreatic tumors are rare occurrences. Arising from the hormone-producing cells, endocrine pancreatic tumors tend to be less aggressive.

The Symptoms of Pancreatic Cancer

What Causes Pancreatic Cancer?

Chronic pancreatitis, diabetes, and obesity are some of the medical conditions that tend to lead to pancreatic cancers. Understanding the medical conditions as well as lifestyle factors is crucial for availing targeted prevention and early intervention strategies.

Risk Factors of Pancreatic Cancer

Risk Factors of Pancreatic Cancer

  • Smoking.
  • Age: Particularly after 45.
  • Family History
  • Genetic Mutations
  • Chronic Pancreatitis
  • Diabetes
  • Obesity

A thorough medical history analysis, including risk factors such as smoking, family history, and genetic predispositions are often the initial clinical validation methodologies used for diagnosing pancreatic cancer. 

  1. Imaging Studies: Radiological techniques such as CT scans, MRIs, and ultrasounds can help obtain detailed images of the pancreas, aiding in the detection of tumors, their size, stage, and potential spread.
  2. Endoscopic Procedures: Endoscopic ultrasound (EUS) is leveraged for a closer examination of the pancreas by inserting a small ultrasound probe through the mouth. Endoscopic retrograde cholangiopancreatography (ERCP) can help identify blockages in the pancreatic or bile ducts.
  3. Biopsy: Definitive diagnosis often requires a tissue sample. Fine-needle aspiration (FNA) or core needle biopsy may be performed during imaging procedures, guiding the extraction of cells for laboratory analysis.
  4. Blood Tests: Elevated levels of certain tumor markers, such as CA 19-9, may be indicative of pancreatic cancer, although these markers lack specificity and can be elevated for other reasons.

Regular monitoring and follow-up assessments further refine the understanding of pancreatic cancer’s progression and response to treatment and management interventions.

 

The treatment of pancreatic cancer varies based on the stage, extent of spread and symptoms.

Stage I and II: Localized Pancreatic Cancer 

Surgery is often considered as the primary approach that aims at complete tumor removal. The Whipple procedure, or pancreatoduodenectomy, may be performed to excise tumors in the head of the pancreas. In some cases, distal pancreatectomy addresses tumors in the body or tail. Adjuvant therapies, like chemotherapy or radiation, may follow surgery to target any remaining cancer cells and reduce the risk of recurrence.

Stage III: Locally Advanced Pancreatic Cancer 

For cases where the pancreatic cancer has spread to nearby blood vessels but remains localized, a combination of chemotherapy and radiation therapy is commonly recommended by the Oncology experts. This approach aims to shrink pancreatic tumors, facilitating potential surgical intervention.

Stage IV: Advanced or Metastatic Pancreatic Cancer 

At this stage, the pancreatic cancer might have already spread to distant organs. The treatment modalities may include:

  • Palliative chemotherapy
  • Targeted therapies
  • Immunotherapy 

These treatment methods essentially focus on managing symptoms and improving the quality of life.

Pancreatic cancer treatment methodologies depend on factors such as tumor stage, location, and the patient’s overall health.

Surgery:
In cases where the cancer is confined to the pancreas and has not spread extensively, surgical interventions become pivotal. The Whipple procedure, distal pancreatectomy, or total pancreatectomy may be considered, aiming to remove the tumor while preserving as much pancreatic function as possible.

Chemotherapy:
Chemotherapy is one of the key systemic therapy interventions. This treatment modality for chemotherapy leverages a combination of drugs to eliminate cancer cells. This treatment can be Adopted before, during and even after a surgical intervention to remove cancer cells from the pancreatic system. Leveraged as a palliative measure for advanced-stage pancreatic cancers.

Radiation Therapy:
Both external beam radiation and internal radiation (brachytherapy) can be employed to target and destroy cancer cells. Radiation may be used in conjunction with surgery or as a standalone treatment.

Targeted Therapies:
Certain medications target specific molecules involved in pancreatic cancer growth. Targeted therapies may be leveraged in combination with chemotherapy to enhance effectiveness or as a standalone treatment.

Immunotherapy:
Enabling your body’s immune system to identify cancer cells and fight them off naturally is at the core of this treatment modality for pancreatic cancer.

Making healthier lifestyle choices and managing the risk factors optimally can help you prevent/manage pancreatic cancer. Quitting smoking significantly reduces the risk, as smoking is a prominent contributor. Maintaining a healthy weight through a balanced diet and regular exercise diminishes the likelihood of developing pancreatic cancer. Limiting alcohol consumption and managing conditions like diabetes, which may increase risk, are also crucial.

While genetic factors play a role, minimizing modifiable risk factors remains key. Routine medical check-ups aid in early detection and intervention.

The survival rate of Pancreatic cancer is at least 5 years after diagnosis.

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Pancreatic cancer presents a challenging prognosis, with a 5-year survival rate of around 10%. Late-stage diagnosis, limited effective treatments, and aggressive tumor behavior contribute to the lower survival rate. 

How Punarjan Clinic Treats Pancreatic Cancer?

How Punarjan Clinic Treats Pancreatic Cancer?

Punarjan Clinic offers a comprehensive and personalized approach to pancreatic cancer treatment, emphasizing the synergy of traditional Ayurvedic principles and modern medical science. The treatment protocol incorporates potent herbal formulations, dietary modifications, and lifestyle adjustments tailored to the individual’s unique constitution.

The Ayurvedic perspective on pancreatic cancer focuses on restoring balance to the body’s doshas, enhancing the immune system, and addressing the root causes of the disease. Herbal remedies, such as Varunadi Kwath and Kachnar Guggulu, are administered to target the specific imbalances associated with pancreatic cancer.

Our approach extends beyond symptom management, encompassing dietary guidelines that support the body’s healing processes. Personalized lifestyle recommendations, including stress management techniques and detoxification strategies, contribute to holistic well-being.

While Ayurveda is complementary to conventional cancer care, it is crucial for individuals to consult with their oncologist and Ayurvedic practitioners for an integrated treatment plan. The transparency and patient-centric approach outlined on their website underscore Punarjan Clinic’s commitment to empowering individuals on their cancer journey with a blend of time-tested Ayurvedic wisdom and modern medical insights.

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Success Stories

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Punarjan Clinic saved my life. When I was told I had eye cancer and needed more tests and chemotherapy, I felt scared. But then I found this hospital.

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Punarjan Clinic has been a ray of hope for Bibi, suffering from Colon cancer. She was told that without tumor removal, survival was unlikely, leaving her unable to eat or drink and in immense pain.

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Frequently Asked Questions

  • What are the early symptoms of pancreatic cancer?

    Early symptoms of pancreatic cancer may include:

    • Abdominal pain
    • Unexplained weight loss
    • Digestive issues.

    You might confuse these symptoms with other health ailments. You should consult your healthcare provider to get a better understanding of your symptoms to seek right treatment.

  • What are the screening tests for pancreatic cancer?

    There are no definitive screening tests to diagnose pancreatic cancer. However, your healthcare provider may recommend genetic testing and other imaging and blood tests to arrive at a conclusive diagnosis.

  • Mention some of the risk factors for pancreatic cancer.

    Medical conditions that can raise your risk of developing pancreatic cancer include:

    • Chronic pancreatitis
    • Diabetes
    • Obesity

    Other risk factors for pancreatic cancer include:

    • Smoking
    • Family history
    • Age
  • How is pancreatic cancer diagnosed?

    Diagnosis involves imaging studies, endoscopic procedures, and biopsy for confirmation. Blood tests, such as CA 19-9, may support the diagnostic process.

  • What treatment options are available for pancreatic cancer?

    Treatment methodologies often recommended for pancreatic cancer include:

    • Surgery
    • Chemotherapy
    • Radiation therapy
    • Targeted therapies
    • Immunotherapy

    The approach depends on the cancer stage and individual factors.

  • Can pancreatic cancer be prevented?

    With lifestyle modifications, such as quitting smoking, maintaining a healthy weight, and managing diabetes may reduce the risk. You should also opt for regular medical check-ups.

  • Are there clinical trials for pancreatic cancer?

    Yes, numerous clinical trials explore innovative treatments. Participation in trials can provide access to cutting-edge therapies and contribute to advancements in pancreatic cancer care.