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Endometrial Cancer

Endometrial Cancer

Endometrial cancer is referred to as the abnormal cell growth in the lining of the uterus, known as the endometrium. While typically diagnosed in postmenopausal women, this cancer variant can affect women of all ages.

Abnormal vaginal bleeding or pelvic pain and other symptoms of endometrial cancer can help you and your healthcare provider diagnose endometrial cancer. Your healthcare provider may leverage medical history scrutiny, physical examinations, and imaging studies to offer a comprehensive diagnosis. Understanding risk factors, such as hormonal imbalances, obesity and other aspects can help you prevent and manage endometrial cancer efficiently.

Treatment modalities, including surgery, radiation, chemotherapy, and hormone therapy, for endometrial cancer are customized to the cancer’s stage and type.

The Types of Endometrial Cancer

Endometrial cancer is primarily categorized into two types:

Type 1 Endometriosis

Type 1 Endometriosis

the most common, is estrogen-dependent and associated with endometrioid histology, often detected at an early stage with a favorable prognosis.

Type 2 Endometriosis

Type 2 Endometriosis

less common, is estrogen-independent and linked to non-endometrioid histology, presenting at advanced stages with a poorer outcome.

Symptoms of Endometrial Cancer

What Causes Endometrial Cancer?

The exact causes of endometrial cancer that occurs due to abnormal growth of cells in the endometrium is yet to be clear. However, certain health conditions, lifestyle choices and other environmental factors may pose as high-risk factors.

Risk Factors of Endometrial Cancer

Risk Factors of Endometrial Cancer

  • Hormonal Imbalances
  • Obesity
  • Diabetes
  • Reproductive Factors
  • Family History
  • Age
  • Tamoxifen Use
  • Lynch Syndrome
  • Polycystic Ovary Syndrome (PCOS)
  • Personal History

Endometrial cancer, when detected early, offers better chances for successful treatment.

  1. Symptom Recognition: Pay attention to potential signs such as abnormal bleeding, pelvic pain, or unexplained weight loss. Timely reporting of symptoms to your healthcare provider is crucial.
  2. Clinical Evaluation: Your healthcare professional will conduct a thorough history and physical examination. Be prepared to discuss your medical history, family history, and any concerning symptoms.
  3. Transvaginal Ultrasound: A transvaginal ultrasound may be performed to visualize the uterus and assess the thickness of the endometrial lining. This non-invasive procedure helps identify potential abnormalities.
  4. Biopsy: If suspicious findings emerge, a biopsy becomes the next step. This involves obtaining a small tissue sample from the endometrium for laboratory analysis. A biopsy provides a definitive diagnosis and helps determine the cancer type and grade.
  5. Hysteroscopy: In some cases, a hysteroscopy may be recommended. This involves inserting a thin, lighted tube through the cervix to directly view the inside of the uterus, allowing for a more detailed assessment.
  6. Imaging Studies: Advanced imaging techniques such as CT scans or MRIs may be employed to evaluate the extent of cancer spread and guide treatment planning.

Stage I: Limited to the Uterus

    • Surgery: The primary treatment is often a hysterectomy, the removal of the uterus. In some cases, a bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes) may be recommended.
    • Lymph Node Assessment: Lymph nodes may be evaluated to determine the extent of cancer spread.
    • Radiation Therapy: Adjuvant radiation may be considered based on specific risk factors.

Stage II: Involvement of Connective Tissues

    • Surgery: Hysterectomy with removal of nearby tissues affected by cancer.
    • Lymph Node Dissection: Extensive lymph node removal may be necessary.
    • Radiation Therapy: To target residual cancer cells and reduce the risk of recurrence.

Stage III: Spread to Pelvic Area

    • Surgery: More extensive surgery may be required, possibly including removal of pelvic lymph nodes or surrounding structures.
    • Radiation Therapy: Often combined with surgery to enhance treatment efficacy.
    • Chemotherapy: In some cases, chemotherapy may be recommended to address potential systemic spread.

Stage IV: Advanced Spread

  • Surgery: In selected cases, surgery may help alleviate symptoms, but it may not be curative.
  • Chemotherapy: Systemic treatment to target cancer cells throughout the body.
  • Hormone Therapy: For cancers that are hormone receptor-positive.
  • Targeted Therapy: Specific drugs may be employed based on molecular characteristics of the cancer.

Treatment approaches may include surgery, radiation, chemotherapy, hormone therapy, or a combination, tailored to the individual’s specific circumstances.

Treatment plans are highly individualized, considering the specific characteristics of the cancer and the patient’s overall health.


    • Hysterectomy: Removal of the uterus is often the primary treatment for early-stage endometrial cancer.
    • Bilateral Salpingo-Oophorectomy: Removal of both ovaries and fallopian tubes may be performed, particularly in postmenopausal women or those with higher-risk tumors.
    • Lymph Node Dissection: Removal and examination of pelvic and para-aortic lymph nodes to assess cancer spread.

Radiation Therapy:

    • External Beam Radiation: Precisely targeted radiation from outside the body to the pelvic area, particularly after surgery.
    • Brachytherapy: Internal radiation involving the placement of radioactive sources directly into or near the tumor site, often used in early-stage cases.


  • Systemic Treatment: Chemotherapy uses drugs to kill or control the growth of cancer cells. It is commonly employed in advanced or recurrent cases and may be combined with surgery or radiation.
  • Adjuvant Chemotherapy: Administered after surgery to eliminate remaining cancer cells.Hormone Therapy:
  • Progesterone Therapy: For certain types of endometrial cancer, hormone therapy with progesterone may be recommended, especially in cases where the cancer is hormone receptor-positive.
  • Targeted Therapy:
  • Molecularly Targeted Drugs: Drugs designed to target specific molecules involved in cancer growth. These may be used in cases with particular genetic or molecular characteristics.
  • Immunotherapy:
  • Enhancing the Immune Response: Immunotherapy drugs can boost the body’s immune system to identify and attack cancer cells.
  • Supportive Care:
  • Pain Management: Addressing pain and discomfort associated with cancer and its treatments.
  • Nutritional Support: Maintaining optimal nutrition during and after treatment.
  • Psychosocial Support: Counseling and support groups to address emotional and mental well-being.

While there is no definitive way to prevent endometrial cancer, several lifestyle choices and risk reduction strategies can help lower the likelihood of its development. Here are some preventive measures:

  • Maintain a Healthy Weight
  • Physical Activity
  • Hormone Replacement Therapy (HRT)
  • Birth Control Pills
  • Pregnancy and Breastfeeding
  • Diabetes Management
  • Healthy Diet
  • Limit Alcohol Consumption:Quit Smoking
  • Regular Check-ups and Screenings
  • Genetic Counseling

The survival rate of Endometrial cancer is at least 5 years after diagnosis.

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The survival rate for Endometrial cancer is promising, with 81% (All SEER stages combined) of patients surviving at least five years after diagnosis. Early detection and advancements in treatment have significantly improved outcomes, offering hope and support to those affected by this condition.

How Punarjan Clinic Treats Endometrial Cancer?

How Punarjan Clinic Treats Endometrial Cancer?

At Punarjan Clinic, our approach to treating endometrial cancer is rooted in the ancient science of Rasayana Ayurveda, aiming not just to alleviate symptoms but to address the underlying causes. Our practitioners meticulously tailor treatment plans after identifying these root causes, ensuring a distinctive and personalized approach.

Our treatment protocol involves a systematic series of herbal medicines, detoxification therapies, specialized diet plans, and lifestyle adjustments. This holistic strategy extends beyond the physical realm, recognizing the emotional and psychological challenges that often accompany cancer diagnoses. Our compassionate environment encourages open communication with well-trained counselors, providing patients a space to express hopes, fears, and worries.

We understand that the doctor-patient connection is sacred, fostering trust and open dialogue. Our comprehensive strategy merges traditional Ayurvedic wisdom with modern diagnostic methods, allowing us to monitor progress and make necessary adjustments.

Choosing Punarjan Clinic is a commitment to the best healing approach, emphasizing the power of nature, individualized care, and a compassionate community. We invite you to embark on a journey towards health, happiness, and a future free from the burden of endometrial cancer, where empowerment and well-being go hand in hand.


Success Stories


Punarjan Clinic saved my life. When I was told I had eye cancer and needed more tests and chemotherapy, I felt scared. But then I found this hospital.

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Punarjan Clinic has been a ray of hope for Bibi, suffering from Colon cancer. She was told that without tumor removal, survival was unlikely, leaving her unable to eat or drink and in immense pain.

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Frequently Asked Questions

  • What are the early signs of endometrial cancer?

    Early signs of endometrial cancer may include abnormal vaginal bleeding, pelvic pain, and changes in bowel or urinary habits. It's crucial to consult a healthcare professional if any concerning symptoms arise.

  • How is endometrial cancer diagnosed?

    Diagnosis typically involves a combination of medical history review, physical examination, transvaginal ultrasound, biopsy, and sometimes imaging studies like CT scans. Consultation with a gynecologic oncologist guides the diagnostic process.

  • What are the risk factors for endometrial cancer?

    Risk factors include hormonal imbalances, obesity, diabetes, early menstruation, late menopause, and a family history of endometrial or colorectal cancers. Understanding these factors helps in preventive measures and early detection.

  • Can endometrial cancer be prevented?

    While prevention is not guaranteed, maintaining a healthy weight, regular exercise, managing diabetes, and discussing hormone replacement therapy with a healthcare provider can lower the risk. Early detection through regular check-ups is crucial.

  • What are the treatment options for endometrial cancer?

    Treatment options include surgery (hysterectomy), radiation therapy, chemotherapy, hormone therapy, targeted therapy, and sometimes a combination of these. The choice depends on the cancer's stage, type, and individual health factors.

  • How effective is endometrial cancer treatment?

    Effectiveness varies based on the cancer's stage and type. Early detection and comprehensive treatment plans often result in favorable outcomes. Regular follow-ups are crucial for monitoring and managing the disease

  • Can endometrial cancer recur after treatment?

    Yes, there is a possibility of recurrence. Regular follow-up appointments help detect any signs of recurrence early. The risk varies among individuals, and personalized care plans are essential.

  • Are there clinical trials for endometrial cancer treatment?

    Yes, clinical trials exploring innovative treatments are ongoing. Participation in these trials may provide access to cutting-edge therapies. Consultation with an oncologist can determine eligibility and suitability for participation.